Articles | Open Access | Vol. 4 No. 12 (2024): Volume 04 Issue 12

ADVANCEMENTS IN PHARMACEUTICAL SUSPENSIONS: FROM RESEARCH TO APPLICATION

Vikram Rathod , Amity Institute of Pharmacy, Amity University, Gwalior, Madhya Pradesh, India

Abstract

Pharmaceutical suspensions are a widely used dosage form, particularly for drugs that are poorly soluble in water. Over the years, significant advancements have been made in the development and optimization of pharmaceutical suspensions to improve their efficacy, stability, and patient compliance. This review aims to provide an overview of recent innovations in pharmaceutical suspension formulations, focusing on the technological, regulatory, and scientific advancements from research to practical application. Key areas discussed include the design of stable and bioavailable suspensions, the use of novel excipients and delivery systems, and emerging technologies such as nanotechnology and smart polymers. Furthermore, the review highlights challenges related to the production, quality control, and patient acceptability of pharmaceutical suspensions. These advancements offer the potential to improve therapeutic outcomes and open new avenues for the administration of poorly soluble drugs.

Keywords

Pharmaceutical suspensions, Drug delivery systems, Stability and bioavailability

References

Atyabi F, Sharma Hl, Mohammad Ha and Fell Jt, Controlled Drug Release From Coated Floating Ion Exchange Resin Beads, Journal Of Controlled Release, 1996; 42:25-28.

Litwin, M, J. Antoniewicz, A. niemirska, A. Wierzbicka, J. Daszkowska, Z.T. Wawer, R.Janas&R.Grenda, Americal Journal Of Hypertension, 2007; 20:875-82.

Billany M R, Suspensions and Emulsions, In Aulton, Me, Editor. Pharmaceutics; the Design and Manufacture of Medicines, 3rd Editionphiladelphia, Churchill Livingstone, 2007; 383-405.

Tripathi, K.D. Essentials of Medical Pharmacology, 3rd Edition, Jaypee Brothers, Newdelhi, 1994; Page No: 441.

R. Brown, R.A. Querica, R. Sigman, Total Nutrient Admixture: A Review, Jpen, 1986; 10: 650-658. 68. L.Mladena, P. Ana, G.K. Svetlene and G.B. Ksenija, Comparision Of Dissolution Profiles and Serum Concentrations of Two Lamotrigine Tablet Formulations; Drugs In R&D, 2011; 53-60.

Nahata M. Lack of Paediatric Drug Formulations. Pediatrics, 1999; 104: 607-609.

Jafar M, Aejaz A, Studies on Ready Mix Suspension of Ampicillin Trihydrate: Development, Characterization and Invitro Evaluation, International Journal of Pharmaceutical Sciences, 2010; 109-12.

Amit Kumar Nayak, Dilip Kumar Pal, Dipti Ranjan Pany, Biswaranjan Mohanty, Journal of Advanced Pharmaceutical Technology& Research, 2010; 338-341.

Ogaji I, Hoag Sw, Effect of Grewia Gum As a Suspending Agent on Ibuprofen Paediatric Formulation, American Association of Pharmaceutical Scientists Pharm Sci Tech, 2011; 07-13.

Femi-Oyewo Mn, Adedokun Mo, Olusoga To, Evaluation of the Suspending Properties of Albizia Zygia Gum on Sulphadimidine Suspension, Tropical Journal of Pharmaceutical Research, 2004; Page No: 279-284.

Anekant J, Yashwant G and Sanjay K.J, Perspectives of Biodegradable Natural Polysaccharides for Site-Specific Drug Delivery To The Colon, Journal of Pharmaceutical Sciences, 2007; 86-128.

Azam Mg and Haider Ss, Evaluation of Dissolution Behaviour of Paracetamol Suspensions, Dhaka University Journal of Pharmaceutical Sciences, 2008; 7:53-8.

Article Statistics

Downloads

Download data is not yet available.

Copyright License

Download Citations

How to Cite

Vikram Rathod. (2024). ADVANCEMENTS IN PHARMACEUTICAL SUSPENSIONS: FROM RESEARCH TO APPLICATION. Frontline Medical Sciences and Pharmaceutical Journal, 4(12), 1–11. Retrieved from https://www.frontlinejournals.org/journals/index.php/fmspj/article/view/641