EXPLORING THE GENETIC LANDSCAPE OF THROMBOSIS RISK IN A SAMPLE OF THE IRAQI POPULATION
Abbas Darwish , Department of Medical Biotechnology/College of Biotechnology/Al-Nahrain University/ Baghdad/ IraqAbstract
Thrombosis is a significant health concern globally, with genetic factors contributing to its development. This study aims to explore the genetic landscape associated with thrombosis risk in a sample of the Iraqi population. Using a case-control design, we analyzed genetic polymorphisms linked to thrombosis, including variations in genes related to coagulation, inflammation, and endothelial function. A total of 300 participants, including 150 individuals with a confirmed history of thrombosis and 150 matched controls, were recruited for this study. Genotyping was performed using polymerase chain reaction (PCR) and sequencing techniques to identify relevant genetic variants. The results revealed several significant associations between specific genetic polymorphisms and increased thrombosis risk in the Iraqi population. Additionally, environmental factors and their interaction with genetic predispositions were examined to provide a comprehensive understanding of thrombosis risk. These findings highlight the importance of genetic screening in identifying individuals at risk of thrombosis and contribute to the growing body of literature on the genetic epidemiology of thrombotic disorders in diverse populations.
Keywords
Thrombosis, Genetic risk factors, Iraqi population
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